ciPTEC-OAT1 Assay Ready Cells
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Description
Pre-differentiated ready-to-use ciPTEC cells.
ciPTEC-OAT 1 based on ciPTEC-parental, including expression and functional uptake via organic anion transporter 1 (OAT1, SLC22A6).
ciPTEC (conditionally immortalised human proximal tubule epitelial cell) is a human renal cell line that mimics the proximal tubule cells of the kidney, expressing key proximal tubular markers
ciPTECs have been stably transfected by SV40T and hTERT, subcloned and well characterized.
Expressing proximal tubular markers alkaline phosphatase, di-peptidiyl peptidase IV and ZO-1. Maintained transport functionality for sodium-dependent phosphate reabsorption, megalin-cubilin receptor-mediated endocytosis, organic cation transport (SLC22A2); p- glycoprotein (ABCB1), multidrug resistance protein 2/4 (MRP2/4), breast cancer resistance protein (ABCG2) and a range of metabolic enzymes.
Additional information
| Shipment Method | World Courier, FedEx |
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