Human drug efflux transporters (ABC transporters) are transiently overexpressed in human embryonic kidney (HEK293) cells. Inside-out membrane vesicles are prepared from these HEK293 cells and used for high-throughput applications. The transporters translocate substrates into membrane vesicles in an ATP-dependent manner. Detection of the substrate inside the vesicles is possible with radiolabel, fluorescence, or LC-MS detection. Cell4Pharma delivers high quality large uniform batches with guaranteed transport ratios.
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Vesicle Kits
Human MRP8 vesicle kit (HEK293 derived)
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Vesicle Kits
Human MRP5 vesicle kit (HEK293 derived)
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Vesicle Kits
Human MRP4 vesicle kit (HEK293 derived)
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Vesicle Kits
Human MRP3 vesicle kit (HEK293 derived)
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Vesicle Kits
Human MRP2 vesicle kit (HEK293 derived)
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Vesicle Kits
Human MRP1 vesicle kit (HEK293 derived)
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Vesicle Kits
Human MDR1 vesicle kit (HEK293 derived)
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Vesicle Kits
Human control vesicle kit (HEK293 derived)
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Vesicle Kits
Human BSEP vesicle kit (HEK293 derived)
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Vesicle Kits
Human BCRP vesicle kit (HEK293 derived)
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